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What is NEMO?
The ubiquity of social exchange and the breakdown of its underlying mechanisms in many neurological and psychiatric disorders make social interaction an important field of study. To fully investigate the link between brain and behavior during a social exchange, it is necessary to simultaneously gather synchronized behavioral and imaging data from each participant.

We call the execution of such simultaneous multi-subject experiments "Hyperscanning". The scarcity of neuroimaging resources limits the ability to perform multi-subject experiments within the same facility, necessitating the ability to simultaneously scan across multiple institutions. Furthermore, in order to correlate behavior and brain activation among participants, sites participating in Hyperscan experiments must be synchronized so that the behavioral and imaging data gathered during the experiment can be reconciled to a common timeline.

Professional software developers at the Human Neuroimaging Laboratory (HNL) have created a distributed framework for executing Hyperscan experiments. The framework, called NEMO, consists of client and server components written in Java, a SQL database for storing experiment metadata and results, an experiment script execution environment based on the Jython scripting language, and pulse-sequence customizations to facilitate network-initiated scanning.

To date, NEMO has been used to execute over 350 instances of 7 different multi-subject experiments, and over 2100 instances of 52 different single-subject experiments.